Quantitative Analysis of Taller than Wide Shape for Patients with Thyroid Nodules.
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- Apr 7, 2018
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Abstract
Objective: A taller than wide (T/W) shape refers to a nodule with an anteroposterior diameter that is longer than the transverse diameter on a transverse, which is a useful feature for diagnosis of thyroid cancer. T/W shape feature, compare to other features, interobserver and intraobserver variability should be less because this is relatively measurable and quantitative. But in truth, the selected length of so-called tall or wide is always operator dependency. New quantitative T/W indexes are proposed here to study the shape of thyroid nodule. The aim of this study was to clarify whether these quantitative T/W indexes are useful for the detection of malignant thyroid nodules.
Methods: Overall, 196 patients with 229 thyroid nodules were included in the final analysis. Quantification of T/W was performed using commercial software (AmCAD-UT; AmCad BioMed, Taiwan). Quantitative T/W indexes includes TTW=ROIY/ROIX, Long Axis/Orthogonal Axis ratio (LO ratio) and tumor orientation angle.
Results: The average value of TTW, LO ratio and orientation angle were 0.685, 0.571 and 0.708, respectively. Ultrasound T/W shape (US-T/W), as assessed..